Friday 3 June 2011

Toxic effects of antibiotics is not super, Germany refractory life-threatening intestinal bacteria

(Berlin 3, Reuters) Chinese scientists have found life in Europe, sweep the 18 outbreaks of E. coli is a super-toxic by a new type of E. coli caused by strains with multiple antibiotic resistance genes, it difficult to treat.
Germany's E. coli outbreak, the Beijing Genomics Institute Shenzhen, China Center for Disease Control and Prevention and other institutions, and a study of Medicine, University of Hamburg, Germany. Genomics Institute of the establishment of a dedicated group of bacteria in samples obtained within 3 days, to complete the genome sequencing of E. coli. After preliminary analysis, the strain is both the invasion and toxin production of EHEC novel, is a STEC serotype O104, but in the past did not lead to large-scale outbreak.

 
African vaccine strain and a similar 02

 
STEC is Shiga toxic E. coli, an intestinal Escherichia coli (EHEC) one of them. European Center for Disease Control (ECDC) has confirmed that this disease caused by the STEC, the bacteria in the past mainly affects children under 5 years old, this is different from most adult infections.

 
Genomics pointed out that the strain of African AIDS patients with diarrhea in 2002, samples of E. coli 55989 strains, over 93% homology. According to gene sequence analysis, the strain by gene transfer, access to EHEC virulence genes, may result in patients with urea fatal hemolytic syndrome (HUS). Due to resistant strains, so that antibiotic treatment ineffective.
German experts, the Cologne, Germany 10 years ago also found that O104 cases, after the bacteria continue to variants significantly enhanced toxicity and drug resistance. Outbreak in Germany in mid-May the outbreak of EHEC infection are worsening, at least nine countries in Europe have suffered outbreaks, 18 people were killed, in addition to Germany, Sweden, who had to tourists, all of the dead from Germany, the infected the number has more than 2,000 people. Apart from outside Germany, Austria, Denmark, France, the Netherlands, Norway, Spain, Sweden, Switzerland and the United Kingdom and other countries there have been the case.
Not found in patients with multiple sources of raw vegetables
Of particular concern is the significant increase in HUS patients, disease control institutions in Germany on Wednesday, the day of HUS cases of severe disease than the day before the national increase of nearly 100, up to 470 cases, is the growth in the most severe cases a month to the day. According to WHO data, HUS symptoms, including acute renal failure, hemolytic anemia and low platelets, the mortality rate of 5%.
Authorities warned that the infection may also spread, but the source of infection is unknown, personal contact can also cause infection, but the current investigation the source of infection mainly in vegetables, so far the survey, were significantly better than those without the disease who eat raw tomatoes , cucumber or lettuce. However, German health and epidemic prevention departments have not so far from any food found to lead to this epidemic strain.
Cooked food can be bactericidal

 
Chinese University Hospital Münster, Germany bacteria expert Zhang WL, said the outbreak HUS month since there are so many cases, unprecedented. She pointed out that this bacterium is highly infectious, can cause infection of 100 bacteria, different from the general to more than 1000 Salmonella can cause infection. But she urged the public not panic, because the heat resistance of EHEC poor water above 70 ℃ in a few minutes of cooking will be able to sterilization.
WHO: a mixture of two strains
World Health Organization said Thursday that initial gene sequencing showed that the current outbreak strain of E. coli in Europe unprecedented strains from two different variants from the new strain.
Ke Luse WHO food safety expert said the new strain more lethal and toxic, which is perhaps why the scale of the epidemic in Europe this the reason such a large and dangerous.
US-3 staining of E. coli was in Germany for suspected
U.S. health officials said Thursday that the United States found that three suspected cases of E. coli infection in Europe, three people went to Germany travel.

 
Reported that the U.S. CDC is currently awaiting test results. 3 found no suspected cases of fatal risk, but the symptoms appeared.

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